Do MSGs Cause Autism?

The idea that MSGs may cause autism has been around for decades, and it is based on a few studies that have suggested a link between the two.

Alan Hollander
September 13, 2023

Do MSGs Cause Autism?

The idea that MSGs may cause autism has been around for decades, and it is based on a few studies that have suggested a link between the two.

What are MSGs?

MSGs are a type of flavor enhancer commonly used in processed and pre-packaged foods. They are made by combining sodium and glutamic acid, which occurs naturally in some foods like tomatoes and cheese. MSGs are often added to foods to enhance their flavor, and they are commonly found in soups, snacks, and fast foods.

What is Autism?

Autism is a neurodevelopmental disorder that affects communication and social interaction. People with autism may have difficulty communicating, interacting with others, or engaging in repetitive behaviors. Autism usually appears in early childhood, and its causes are not fully understood.

The Controversy Surrounding MSGs and Autism

The idea that MSGs may cause autism has been around for decades, and it is based on a few studies that have suggested a link between the two. However, these studies have been criticized for their small sample sizes, lack of control groups, and other methodological flaws.

One study that is often cited by those who believe that MSGs cause autism is a 1969 study in which researchers injected newborn mice with high doses of MSGs.

The mice developed brain lesions and showed signs of behavioral problems, which some people have interpreted as evidence that MSGs are harmful to the developing brain. However, this study used very high doses of MSGs that are not typically found in human food, and it has not been replicated in humans.

The Science Behind MSGs and Autism

Despite the controversy surrounding MSGs and autism, the scientific evidence on this topic is inconclusive. Some studies have suggested a link between MSGs and autism, while others have found no association.

One study published in the Journal of Autism and Developmental Disorders in 2017 found that children with autism were more likely to have consumed MSGs during pregnancy than children without autism. However, this study relied on self-reported dietary data, which may not be accurate.

Another study published in the Journal of Nutritional Biochemistry in 2018 found that rats fed a diet high in MSGs showed signs of oxidative stress, which is a type of cellular damage that has been linked to autism. However, this study was conducted in animals, and its relevance to humans is unclear.

The Potential Health Effects of Consuming MSGs

While the link between MSGs and autism is still up for debate, there are some potential health effects associated with consuming large amounts of MSGs. For example, some studies have suggested that MSGs may contribute to weight gain and obesity by stimulating appetite and increasing food intake.

Additionally, some people may be sensitive to MSGs and experience symptoms like headaches, nausea, and flushing when they consume foods containing this ingredient. This condition is known as "MSG sensitivity" or "Chinese restaurant syndrome."

However, the vast majority of people can consume moderate amounts of MSGs without experiencing any negative health effects. The U.S. Food and Drug Administration (FDA) considers MSGs to be safe for consumption, and it has classified them as a generally recognized as safe (GRAS) ingredient.

As with any food additive, it's a good idea to consume MSGs in moderation and pay attention to how your body reacts to them. If you experience any adverse symptoms after consuming foods containing MSGs, you may want to avoid this ingredient in the future or speak with a healthcare professional about your concerns.

The FDA's Regulations and Guidelines Regarding MSGs

The U.S. Food and Drug Administration (FDA) regulates the use of MSGs in food products. According to the FDA, MSGs are generally recognized as safe (GRAS) when used in accordance with good manufacturing practices.

The FDA requires that food manufacturers list MSGs on their ingredient labels if they are added to a product as a flavor enhancer. However, MSGs may also be present in some natural flavorings, and in these cases, they do not need to be listed separately on the label.

In addition to requiring accurate labeling, the FDA sets limits on the amount of MSGs that can be added to certain foods. For example, the FDA prohibits the use of MSGs in infant formula, and it limits the amount of this ingredient that can be added to other foods like meat products and soups.

Overall, the FDA considers MSGs to be safe for consumption when used appropriately. However, if you have concerns about consuming this ingredient or experience adverse symptoms after consuming foods containing MSGs, you may want to speak with a healthcare professional or avoid this ingredient altogether.

How to Identify MSGs on Food Labels?

Reading food labels is an important step in identifying whether a product contains MSGs. Here are some tips for reading food labels to help you identify products that contain this ingredient:

Look for "Monosodium Glutamate" on the Ingredient List

The most straightforward way to identify whether a product contains MSGs is to look for "monosodium glutamate" on the ingredient list. If this ingredient is present, it means that the product contains MSGs.

Check for Other Ingredients That Contain Glutamate

While monosodium glutamate is the most common form of glutamate used as a flavor enhancer, there are other ingredients that also contain glutamate. These include hydrolyzed vegetable protein, autolyzed yeast extract, and sodium caseinate. If any of these ingredients are listed on the label, it's possible that the product contains MSGs.

Be Aware of Hidden Sources of MSGs

In addition to being added directly to foods as a flavor enhancer, MSGs can also be found in some natural flavorings and seasonings. For example, soy sauce often contains high levels of naturally occurring glutamates, which can have a similar effect as added MSGs.

Look for Products Labeled "MSG-Free"

Some food manufacturers may choose to label their products as "MSG-free" if they do not contain any added monosodium glutamate or other ingredients that contain glutamates. While this labeling is not regulated by the FDA, it can be a helpful tool when trying to avoid foods containing MSGs.

By following these tips and reading food labels carefully, you can make informed decisions about which products to choose when shopping for groceries. However, it's important to remember that small amounts of MSGs are generally considered safe for consumption by the FDA and do not pose a significant health risk for most people.

Environmental Factors and the Risk of Autism

While the exact causes of autism are not fully understood, research suggests that both genetic and environmental factors may play a role. Environmental factors can include things like exposure to toxins, infections during pregnancy, and maternal stress.

One study published in JAMA Pediatrics in 2019 found that exposure to air pollution during pregnancy was associated with an increased risk of autism in children. The study analyzed data from over 100,000 mother-child pairs and found that exposure to particulate matter and nitrogen dioxide during pregnancy was linked to a higher risk of autism.

Other studies have suggested that prenatal exposure to pesticides may also increase the risk of autism. For example, a study published in Environmental Health Perspectives in 2018 found that pregnant women who lived near agricultural areas where pesticides were used had a higher risk of having a child with autism.

Maternal stress has also been linked to an increased risk of autism. One study published in JAMA Psychiatry in 2013 found that mothers who experienced high levels of stress during pregnancy were more likely to have children with autism.

While more research is needed to fully understand the impact of environmental factors on the risk of developing autism, these studies suggest that reducing exposure to toxins and pollutants during pregnancy may help lower this risk. Additionally, managing stress levels during pregnancy may also be important for reducing the risk of autism.

The Role of Genetics in the Development of Autism

While environmental factors may play a role in the development of autism, genetics are also thought to be a significant contributing factor. Studies have found that families with one child with autism are more likely to have another child with the condition, and identical twins are more likely to both have autism than fraternal twins.

Research has identified several genes that may be associated with an increased risk of developing autism. For example, mutations in the SHANK3 gene have been linked to an increased risk of developing autism spectrum disorder. This gene plays a role in the development and function of synapses, which are connections between neurons in the brain.

Other genes that have been linked to autism include those involved in communication between brain cells and those that regulate brain development. However, there is no single "autism gene," and the condition is likely caused by a combination of genetic factors.

While genetics may play a role in the development of autism, it's important to remember that not all individuals with genetic risk factors will develop the condition. Additionally, many individuals diagnosed with autism do not have any known genetic mutations or abnormalities.

Overall, while much research still needs to be done on both environmental and genetic factors contributing to autism, current evidence suggests that both play a critical role in its development.

Alternative Flavor Enhancers to MSGs

While MSGs are commonly used as a flavor enhancer in processed and pre-packaged foods, there are alternative ingredients that can be used to achieve a similar effect. Here are some examples of alternative flavor enhancers that you may want to try:

Yeast Extract

Yeast extract is a natural ingredient made from yeast cells that have been broken down into a paste or powder. It contains naturally occurring glutamates, which can enhance the flavor of foods without the need for added MSGs. Yeast extract is commonly used in soups, sauces, and snack foods.

Soy Sauce

Soy sauce is a popular condiment made from fermented soybeans, wheat, salt, and water. It contains naturally occurring glutamates and can be used as a substitute for MSGs in many recipes. Soy sauce is commonly used in Asian cuisine but can also be used to add flavor to other dishes like stir-fries and marinades.

Parmesan Cheese

Parmesan cheese is a hard Italian cheese that has a strong umami flavor thanks to its high levels of glutamate. Adding grated Parmesan cheese to soups, pastas, and other dishes can enhance their flavor without the need for added MSGs.

Miso Paste

Miso paste is a traditional Japanese ingredient made from fermented soybeans, rice or barley, salt, and koji (a type of fungus). It has a savory umami flavor and can be used as a seasoning for soups, marinades, dressings, and more.

By using these alternative ingredients as flavor enhancers instead of MSGs, you can still enjoy deliciously flavorful meals while avoiding potential health risks associated with consuming large amounts of MSGs.

FAQs

What is monosodium glutamate (MSG)?

Monosodium glutamate (MSG) is a flavor enhancer commonly used in processed and pre-packaged foods. It is made by combining sodium and glutamic acid, which is an amino acid found naturally in many foods.

What are some common foods that contain MSGs?

MSGs can be found in a wide variety of foods, including canned soups, snack foods, frozen dinners, and salad dressings. They are also commonly used in Asian cuisine as a seasoning for meats, vegetables, and sauces.

Can consuming large amounts of MSGs cause health problems?

Some studies have suggested that consuming large amounts of MSGs may contribute to weight gain and obesity by stimulating appetite and increasing food intake. Additionally, some people may be sensitive to MSGs and experience symptoms like headaches, nausea, and flushing when they consume foods containing this ingredient.

Are there any regulations regarding the use of MSGs in food products?

The U.S. Food and Drug Administration (FDA) regulates the use of MSGs in food products. According to the FDA, MSGs are generally recognized as safe (GRAS) when used in accordance with good manufacturing practices. The FDA requires that food manufacturers list MSGs on their ingredient labels if they are added to a product as a flavor enhancer.

Is there any evidence linking MSG consumption during pregnancy to autism?

While some studies have suggested a link between consuming MSGs during pregnancy and an increased risk of autism in children, the scientific evidence on this topic is inconclusive. More research is needed to fully understand the potential impact of consuming MSGs during pregnancy on fetal development.

What are some alternative flavor enhancers to using MSGs?

There are several alternative ingredients that can be used to enhance the flavor of foods without the need for added MSGs. These include yeast extract, soy sauce, Parmesan cheese, and miso paste. By using these alternative ingredients as flavor enhancers instead of MSGs, you can still enjoy deliciously flavorful meals while avoiding potential health risks associated with consuming large amounts of MSGs.

Conclusion

In conclusion, the evidence on whether MSGs cause autism is mixed, and there is no clear consensus on this issue. While some studies have suggested a link between MSGs and autism, others have found no association. If you are concerned about the potential health effects of MSGs, you may want to limit your intake of processed and pre-packaged foods.

However, MSGs are generally recognized as safe by the FDA, and they are not known to cause autism. As with any health concern, it is always a good idea to consult with a healthcare provider if you have questions or concerns.

References

https://www.msgtruth.org/msg-autism

https://www.abbeyskitchen.com/does-msg-cause-headaches-autism/

https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/expert-answers/monosodium-glutamate/faq-20058196

https://leafwingcenter.org/avoid-foods-autism/

https://worldstemcellsclinic.com/blog/eating-for-autism-food-additives-that-destroy-the-gut/